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Contributor Information

  • Name Leiping Chen
  • Institute Yale University

Tool Details

  • Tool name: Anti-Fibrinogen-like Protein 1 [177 m01]
  • Alternate names: FGL-1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA
  • Description: Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.
  • Isotype: IgG1 kappa
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: Fibrinogen-like Protein 1
  • Target background: Fibrinogen-like Protein 1 (FLG-1) is secreted liver protein and inhibits antigen-specific T cell activation. FLG-1 binds to lymphocyte-activation gene 3 (LAG3), independent from MHC-Class II. FLG-1 ablation in mice promotes T cell immunity. FLG1 is shown to be highly produced in cancer cells.

Application Details

  • Application: ELISA

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Wang et al. 2019. Cell. 176(1-2):334-347.e12. PMID: 30580966.