ANTIBODIES
Contributor Information
- Institute A*STAR Accelerate Technologies Pte Ltd
Tool Details
- Tool name: Anti-SGT [6A4]
- Clone: 6A4
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: IF ; WB
- Description: The small glutamine-rich tetratricopeptide repeat (SGT) containing protein, also known as viral protein U (Vpu)-binding protein, was identified as a host protein that interacted with the non-structural (NS) protein of parvovirus. A subsequent study showed that SGT interacts with human immunodeficiency virus-1 (HIV-1) Vpu and Gag proteins, suggesting that SGT may play a role in HIV-1 virus assembly or release. Recently, it has been shown to interact with the SARS-CoV 7a protein but the biological significance of the interaction between 7a and SGT remains to be elucidated.
- Immunogen: GST-SGT fusion protein
- Isotype: IgG1
- Research area: Apoptosis and autophagy; Cell biology; Cell signaling and signal transduction; Microbiology
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Small glutamine-rich TPR-repeat containing protein
- Target background: The small glutamine-rich tetratricopeptide repeat (SGT) containing protein, also known as viral protein U (Vpu)-binding protein, was identified as a host protein that interacted with the non-structural (NS) protein of parvovirus. A subsequent study showed that SGT interacts with human immunodeficiency virus-1 (HIV-1) Vpu and Gag proteins, suggesting that SGT may play a role in HIV-1 virus assembly or release. Recently, it has been shown to interact with the SARS-CoV 7a protein but the biological significance of the interaction between 7a and SGT remains to be elucidated.
Application Details
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
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