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Contributor Information

  • Name Ron Laskey
  • Institute University of Cambridge

Tool Details

  • Tool name: Anti-v-Myb/c-Myb [4E3]
  • Alternate names: cmyb; myb; v-myb myeloblastosis viral oncogene homolog; c-myb; xmyb
  • Clone: 4.00E+03
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse ; Xenopus laevis
  • Host: Mouse
  • Application: IP ; WB
  • Description: v Myb/c Myb is a transcriptional activator; DNA binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. It plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed primarily in haematopoietic cells and immature gastroepithelial cells.
  • Immunogen: Recombinant v-myb protein.
  • Isotype: IgG2a
  • Research area: Microbiology; Immunology

  • For Research Use Only

Target Details

  • Target: v-Myb + c-Myb 
  • Target background: v Myb/c Myb is a transcriptional activator; DNA binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. It plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed primarily in haematopoietic cells and immature gastroepithelial cells.

Application Details

  • Application: IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Benes et al. 2007. Leuk Res. 31(10):1421-31. PMID: 17624428.
  •   Zhang et al. 2007. Arterioscler Thromb Vasc Biol. 27(8):1760-7. PMID: 17478756.