ANTIBODIES

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Anti-IgM

Cat. #158052

Tool name: Anti-IgM
Tool type: Antibodies
Tool sub-type: Secondary Antibody
Class: Polyclonal
Conjugate: Unconjugated
Reactivity: Pangasius Catfish
Host: Rabbit
Cancer type: Broadly Applicable
Molecular weight of the target: 68 kDa
Application: ELISA
Description: IGHM (Immunoglobulin heavy constant Mu) is a protein coding gene. The IGHM gene encodes the C region of the mu heavy chain, which defines the Immunoglobulin (Ig) M isotype. Immunoglobulin is membrane-bound or is secreted as glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulin serves as a receptor which, upon binding of a specific antigen, triggers the clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. Secreted immunoglobulin mediates the effector phase of humoral immunity, which results in the elimination of bound antigens. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood-stocks health testing. This anti-IgM antibody provides a useful tool to monitor brood stock health and vaccine efficacy in fish and will assist in the development of future vaccines.
Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is specific to Pangasius catfish specie.
Research area: Cell biology; Immunology

Target: Immunoglobulin Heavy Constant Mu (IgM)
Target molecular weight: 68 kDa
Target background: IGHM (Immunoglobulin heavy constant Mu) is a protein coding gene. The IGHM gene encodes the C region of the mu heavy chain, which defines the Immunoglobulin (Ig) M isotype. Immunoglobulin is membrane-bound or is secreted as glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulin serves as a receptor which, upon binding of a specific antigen, triggers the clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. Secreted immunoglobulin mediates the effector phase of humoral immunity, which results in the elimination of bound antigens. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood-stocks health testing. This anti-IgM antibody provides a useful tool to monitor brood stock health and vaccine efficacy in fish and will assist in the development of future vaccines.

£ 300
This fee is applicable only for non-profit organizations

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