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Contributor Information

  • Name Abdo Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-IFNg
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Salmonids
  • Host: Rabbit
  • Molecular weight of the target: 18 kDa
  • Application: ELISA ; IHC ; WB
  • Description: IFN-? is a key cytokine involved in Th1 immune responses. It is mainly produced by T cells and NK cells, and drives both innate and adaptive immunity systems that promote protection against intracellular infections. IFN-? is involved in activation of macrophages and T helper lymphocytes, stimulation of antigen presentation, control of cell proliferation and apoptosis, induction of antiviral state, immunomodulation, inflammation and leucocyte trafficking. IFN-? is one of the most important cytokines in both innate and adaptive immune responses; therefore accurate assessment of IFN-? levels is of critical importance in evaluating the status of the immune system. An IFN-? antibody would be particularly useful in examining immune responses in fish to infectious agents and in the development of protective responses after vaccination.
  • Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in salmonids fish species.
  • Research area: Cell biology; Immunology

  • For Research Use Only

Target Details

  • Target: Interferon gamma
  • Target molecular weight: 18 kDa
  • Target background: IFN-? is a key cytokine involved in Th1 immune responses. It is mainly produced by T cells and NK cells, and drives both innate and adaptive immunity systems that promote protection against intracellular infections. IFN-? is involved in activation of macrophages and T helper lymphocytes, stimulation of antigen presentation, control of cell proliferation and apoptosis, induction of antiviral state, immunomodulation, inflammation and leucocyte trafficking. IFN-? is one of the most important cytokines in both innate and adaptive immune responses; therefore accurate assessment of IFN-? levels is of critical importance in evaluating the status of the immune system. An IFN-? antibody would be particularly useful in examining immune responses in fish to infectious agents and in the development of protective responses after vaccination.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
  • Shipping conditions: Shipping at 4°C

Documentation