ANTIBODIES

Contributor Information
- Name Abdo Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-SAA5 [A10 P4F7*C9]
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Salmonids
- Host: Mouse
- Molecular weight of the target: 13
- Application: ELISA ; IHC ; WB
- Strain: Balb/c
- Description: Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA1-3). SAA proteins also exhibit significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as a potential target in the treatment of diseases associated with inflammation. In salmon, SAA-5 has been indicated as a main acute phase response (APR) protein post 24 h in which SAA-5 is significantly induced in liver. This is a significant health marker.
- Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in salmonids fish species.
- Isotype: IgG1 kappa
- Research area: Cell biology; Immunology
- For Research Use Only
Target Details
- Target: Serum amyloid A-5 (SAA5)
- Target molecular weight: 13
- Target background: Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA1-3). SAA proteins also exhibit significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as a potential target in the treatment of diseases associated with inflammation. In salmon, SAA-5 has been indicated as a main acute phase response (APR) protein post 24 h in which SAA-5 is significantly induced in liver. This is a significant health marker.
Application Details
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Storage buffer:
- Storage conditions:
- Shipping conditions: Shipping at 4ðC