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Contributor Information

  • Name Paul Knox
  • Institute University of Leeds

Tool Details

  • Tool name: Anti-Arabinogalactan-protein [LM2]
  • Alternate names: Rice (Oryza Sativa) arabinogalactan-proteins
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Host: Rat
  • Description: Arabinogalactan-proteins (AGPs) are a class of abundant proteoglycans found at the plant cell surface and are predominantly associated with the plasma membrane and extracellular secretions. Although the functions of AGPs are unknown it has been speculated that they may have roles as lubricants, in nutrition or in some aspect of plant cell recognition (Clarke et al, 1979; Fincher et al, 1983; Chasan, 1994). The addition of isolated AGPs to carrot cell cultures has been reported to influence development (Kreuger and van Hoist, 1993), and AGPs have been implicated in the control of plant cell proliferation (Basile and Basile, 1993; Serpe and Nothnagel, 1994). The generation and use of monoclonal antibodies recognizing arabinogalactan-proteins has demonstrated the extensive regulation of AGP carbohydrate epitopes in relation to early stages of cell development in roots, shoots and embryos further implicating this class of plant cell surface molecule in aspects of plant cell development (Knox et al, 1989; Pennell and Roberts, 1990; Stacey et al, 1990; Knox et al, 1991; Pennell et al, 1991; Schindler et al, 1995)
  • Research area: Plant Science

  • For Research Use Only

Target Details

  • Target: Arabinogalactan-protein
  • Target background: Arabinogalactan-proteins (AGPs) are a class of abundant proteoglycans found at the plant cell surface and are predominantly associated with the plasma membrane and extracellular secretions. Although the functions of AGPs are unknown it has been speculated that they may have roles as lubricants, in nutrition or in some aspect of plant cell recognition (Clarke et al, 1979; Fincher et al, 1983; Chasan, 1994). The addition of isolated AGPs to carrot cell cultures has been reported to influence development (Kreuger and van Hoist, 1993), and AGPs have been implicated in the control of plant cell proliferation (Basile and Basile, 1993; Serpe and Nothnagel, 1994). The generation and use of monoclonal antibodies recognizing arabinogalactan-proteins has demonstrated the extensive regulation of AGP carbohydrate epitopes in relation to early stages of cell development in roots, shoots and embryos further implicating this class of plant cell surface molecule in aspects of plant cell development (Knox et al, 1989; Pennell and Roberts, 1990; Stacey et al, 1990; Knox et al, 1991; Pennell et al, 1991; Schindler et al, 1995)

Application Details

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Yates et al. 1996. Glycobiology. 6(2):131-9. PMID: 8727785.