ANTIBODIES
Contributor Information
- Name Kaisa Ivaska-Papaioannou ; Urpo LamminmĤki
- Institute University of Turku
Tool Details
- Tool name: Anti-uncarboxylated osteocalcin (ucOC) [Fab-13]
- Alternate names: Uncarboxylated osteocalcin, uc-Osteocalcin, uc-OC, bone gamma-carboxyglutamic acid-containing protein, BGLAP
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Cancer type: Genitourinary cancer
- Application: IF ; Fn
- Description: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin. Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation. Uncarboxylated osteocalcin (ucOC) may participate in the regulation of glucose metabolism, thus measurement of ucOC could be useful in evaluating interactions between bone and glucose metabolism.
- Immunogen: Human full-length ucOC peptide (149, Glu at positions 17, 21 and 24; C23C29 bridge)
- Isotype: IgG1 kappa
- Research area: Disease (not cancer); Metabolism
- For Research Use Only
Target Details
- Target: osteocalcin - partially carboxylated with Glu at position 17 and 21
- Target background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a small (49-amino-acid) noncollagenous protein hormone found in bone and dentin. Osteocalcin is a bone-specific protein which contains three glutamic acid residues (Glu) that undergo post-translational gamma-carboxylation. Uncarboxylated osteocalcin (ucOC) may participate in the regulation of glucose metabolism, thus measurement of ucOC could be useful in evaluating interactions between bone and glucose metabolism.
Application Details
- Application: IF ; Fn
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4Ă°C
Documentation
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