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Contributor Information

  • Institute Netherlands Cancer Institute

Tool Details

  • Tool name: Anti-Keratin 14 [SPK14]
  • Alternate names: KRT14; Keratin 14
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Pig ; Feline
  • Host: Mouse
  • Molecular weight of the target: 51 kDa
  • Application: FACS ; IHC ; WB
  • Strain: Balb/c
  • Description: Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations
  • Immunogen: Mouse was immunized with a synthetic peptide corresponding to the carboxy-terminal sequence of human cytokeratin 14 (KVVSTHEQVLRTKN) coupled to keyhole limpet hemocyanin.
  • Isotype: IgG1
  • Research area: Cell biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Keratin14
  • Target molecular weight: 51 kDa
  • Target background: Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. Cytokeratin 14 is usually found as a heterodimer with type II keratin 5 and form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex and dermatopathia pigmentosa reticularis, both of which are autosomal dominant mutations

Application Details

  • Application: FACS ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Ivanyi et al. 1993. Am J Vet Res. 54(7):1095-102. PMID: 7690208.
  •   Ivanyi et al. 1992. Am J Vet Res. 53(3):304-14. PMID: 1375818.