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Contributor Information

  • Institute Yale University

Tool Details

  • Tool name: Anti-ICOS [4A.3A2]
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Cancer type: Digestive / Gastrointestinal cancer
  • Description: Monoclonal antibody directed against ICOS, an immune checkpoint inhibitor. Background and Research Application ICOS (Inducible T-cell CO Stimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is an immune checkpoint expressed on activated T cells, which has opposing functions in sustaining T cell activation and in Treg suppressive activity. ICOS plays roles in cell-cell signalling, immune responses and regulation of cell proliferation.
  • Immunogen: Q9Y6W8
  • Immunogen UniProt ID: Q9Y6W8
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: inducible T-cell co-stimulator, CD278
  • Target background: Monoclonal antibody directed against ICOS, an immune checkpoint inhibitor. Background and Research Application ICOS (Inducible T-cell CO Stimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is an immune checkpoint expressed on activated T cells, which has opposing functions in sustaining T cell activation and in Treg suppressive activity. ICOS plays roles in cell-cell signalling, immune responses and regulation of cell proliferation.

Application Details

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

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