ANTIBODIES
Contributor Information
- Institute Netherlands Cancer Institute
Tool Details
- Tool name: Anti-CD39 (ENTPD1) [R22]
- Alternate names: Ectonucleoside Triphosphate Diphosphohydrolase; Ecto-ATPDase
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Rat
- Molecular weight of the target: 78 kDa
- Application: FACS
- Strain: Balb/c
- Description: CD39 is a typical cell surface-located enzymes with an extracellularly facing catalytic site. It is an ectonucleotidase that catalyse the hydrolysis of ÄÂ?- and ÄÂ?-phosphate residues of triphospho- and diphosphonucleosides to the monophosphonucleoside derivative. For example, it hydrolyses P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. It can therefore affect P2 receptor activation and functions
- Immunogen: JY cells
- Isotype: IgG1
- Research area: Cell signaling and signal transduction
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: CD39
- Target molecular weight: 78 kDa
- Target background: CD39 is a typical cell surface-located enzymes with an extracellularly facing catalytic site. It is an ectonucleotidase that catalyse the hydrolysis of ?- and ?-phosphate residues of triphospho- and diphosphonucleosides to the monophosphonucleoside derivative. For example, it hydrolyses P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. It can therefore affect P2 receptor activation and functions
Application Details
- Application: FACS
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Gouttefangeas et al. 1992. Eur J Immunol. 22(10):2681-5. PMID: 1396972.
- • Kansas et al. 1991. J Immunol. 146(7):2235-44. PMID: 1672348.
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