ANTIBODIES
Contributor Information
- Institute Netherlands Cancer Institute
Tool Details
- Tool name: Anti-CD63 [LAMP3]
- Alternate names: Melanoma-Associated Antigen ME491; Tetraspanin-3; Granulophysin
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 25 kDa
- Application: ELISA ; IHC ; IP
- Strain: Balb/c
- Description: CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced.
- Immunogen: Purified membranes of human melanoma cells
- Isotype: IgG1
- Research area: Cell biology
- Myeloma used: P3X63Ag8
- For Research Use Only
Target Details
- Target: CD63
- Target molecular weight: 25 kDa
- Target background: CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced.
Application Details
- Application: ELISA ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
References
- • Hagen et al. 1986. Histopathology. 10(7):689-700. PMID: 2427431.
- • Palmer et al. 1985. Pathology. 17(2):335-9. PMID: 3900899.
- • Vennegoor et al. 1985. Int J Cancer. 35(3):287-95. PMID: 3882581.
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