Product Image

Contributor Information

  • Institute Netherlands Cancer Institute

Tool Details

  • Tool name: Anti-cErbB2/HER2 [9G6]
  • Alternate names: NEU
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 185 kDa
  • Application: EM (EM) ; FACS ; IHC ; IF ; IP ; WB
  • Description: HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients
  • Immunogen: protein.
  • Isotype: IgG1
  • Research area: Cancer; Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: cErbB2/HER-2
  • Target molecular weight: 185 kDa
  • Target background: HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients

Application Details

  • Application: EM (EM) ; FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-CD45RA [BU82]

#153226
Product Image

Anti-Influenza A NP [HB65]

#153522
Product Image

Anti-Striated Muscle Troponin I [42/25]

#151600

References

  • •  van de Vijver et al. 1988. N Engl J Med. 319(19):1239-45. PMID: 2903446.