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Contributor Information

  • Name Margaret Goodall
  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-CD45RA [BU82]
  • Alternate names: Protein tyrosine phosphatase receptor type C; PTPRC;
  • Clone: BU82
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC
  • Strain: Balb/c
  • Description: CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells.
  • Immunogen: Germinal centre B cells
  • Isotype: IgG2a
  • Research area: Cell biology; Immunology; Stem cell biology

  • For Research Use Only

Target Details

  • Target: CD45RA
  • Target background: CD45 is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45RA is an isoform of the CD45 complex which is selectively expressed on B cells.

Application Details

  • Application: IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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