ANTIBODIES
Contributor Information
- Institute Hudson Institute Of Medical Research
Tool Details
- Tool name: HtrA3 (Clone 2C4)
- Alternate names: HtrA3
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
- Application: WB
- Strain: Balb/c
- Description: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
- Immunogen: synthetic peptide TIKIHPKKKL (corresponding to residues 230-239 in both HtrA3-L and HtrA3-S
- Immunogen UniProt ID: P83110, HTRA3_HUMAN
- Research area: Tissue-specific biology
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Human HtrA3 (high temperature requirement factor A)
- Target molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
- Target background: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
Application Details
- Application: WB
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • 25248123
- • 27932697
- • HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening.
- • Dynon et al. 2012. PLoS One. 7(9):e45956. PMID: 23049902.
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