ANTIBODIES
Contributor Information
- Name Royal McGraw
- Institute University of Georgia
Tool Details
- Tool name: Anti-TNF-a [6H4.E1]
- Alternate names: TNF-?
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Horse
- Host: Mouse
- Application: WB ; ELISA ; IP
- Description: Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer's and cancer.
- Immunogen: Protein
- Isotype: IgG2b
- Research area: Cell signaling and signal transduction; Apoptosis and autophagy
- For Research Use Only
Target Details
- Target: Tumor Necrosis Factor- alpha
- Target background: Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer's and cancer.
Application Details
- Application: WB ; ELISA ; IP
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4Ă°C
Documentation
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