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Contributor Information

  • Institute BioServ UK Ltd

Tool Details

  • Tool name: Anti-Myostatin [Myo2/1A]
  • Alternate names: Growth/differentiation factor 8, GDF-8, myostatin, GDF8, MSTN
  • Clone: Myo2/1A
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 52 kDa
  • Application: WB
  • Description: Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis.
  • Immunogen: Recognizes the 113 amino acid carboxy-terminal fragment of Myostatin protein
  • Research area: Cell signaling and signal transduction
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Myostatin
  • Target molecular weight: 52 kDa
  • Target background: Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis.

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Artaza et al. 2005. Endocrinology. 146(8):3547-57. PMID: 15878958.
  • •  Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells.