ANTIBODIES

Contributor Information
- Institute BioServ UK Ltd
Tool Details
- Tool name: Anti-Inhibin a [PO12/8]
- Alternate names: Inhibin alpha chain, INHA
- Clone: PO12/8
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 40 kDa
- Application: ELISA ; IHC
- Strain: Balb/c
- Description: Higher levels of inhibin ÄÂ? have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin ÄÂ? levels, especially in prostate cancer cells.
- Immunogen: Synthetic peptide corresponding to epitope region aa73-96 of the aC region of a subunit of inhibin A
- Isotype: IgG2a
- Research area: Cancer; Cell signaling and signal transduction
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Inhibin a
- Target molecular weight: 40 kDa
- Target background: Higher levels of inhibin a have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin a levels, especially in prostate cancer cells.
Application Details
- Application: ELISA ; IHC
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Balanathan et al. 2009. Br J Cancer. 100(11):1784-93. PMID: 19436293.
- • Elevated level of inhibin-alpha subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer.
- • Risbridger et al. 2004. Mol Cell Endocrinol. 225(1-2):73-6. PMID: 15451570.
- • Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer.
- • Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.
- • Development of an inhibin alpha subunit ELISA with broad specificity.