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Contributor Information

  • Institute BioServ UK Ltd

Tool Details

  • Tool name: Anti-Myelin Basic Protein (region 119-131) [MBP2]
  • Alternate names: Myelin basic protein, MBP, 2 kDa microtubule-stabilizing protein, Myelin A1 protein
  • Clone: MBP2
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Bovine ; Human ; Guinea Pig ; Pig ; Rat ; Rabbit ; Sheep
  • Host: Mouse
  • Cancer type: Neurological cancer
  • Molecular weight of the target: 13-21 kDa
  • Application: ELISA ; IHC ; IF ; IP ; WB
  • Description: Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.
  • Immunogen: Recognises bovine MBP, in the region of residues 119-131 (GAEGQRPGFGYGG)
  • Isotype: IgG1
  • Research area: Cell biology; Immunology; Neurobiology
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: Myelin Basic Protein (region 119-131)
  • Target molecular weight: 13-21 kDa
  • Target background: Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.

Application Details

  • Application: ELISA ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

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References

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  • •  Expression of hemoglobin in rodent neurons.
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  • •  Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
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  • •  Monoclonal antibodies reactive with myelin basic protein.
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  • •  Region-specific immunoassays for human myelin basic protein.
  • •  Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.
  • •  Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.