ANTIBODIES

Contributor Information
- Name RubĂŠn Vicente, Pilar Rivera
- Institute Universitat Pompeu Fabra
- Primary citation Li et al. 2007. Proc Natl Acad Sci U S A. 104(47):18636-41. PMID 18003899.
Tool Details
- Tool name: Anti-ZIP4 antibody
- Clone: 33
- Tool type: Antibody
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Reactivity: Human
- Host: Mouse
- Cancer type: Pancreatic cancer
- Disease: Acrodermatitis enteropathica
- Application: Western Blottting, Immunostaining
- Strain: Patent protected: EP20382172A¡2020-03-10, US 17/909,885. EP3878473A1, EP21709731A, EP2021056036W.
- Description: Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. ZIP4 is overexpressed in human pancreatic cancer and contributes to tumor progression by accumulation of intracellular zinc and stimulation of cell proliferation, endothelial mesenchymal transition and cancer progression.
- Isotype: IgG
- Research area: Cancer
- For Research Use Only
Target Details
- Target: Zinc Transporter ZIP4
- Target background: Zinc transporter ZIP4 is a transmembrane protein which in humans is encoded by the SLC39A4 gene. ZIP4 is overexpressed in human pancreatic cancer and contributes to tumor progression by accumulation of intracellular zinc and stimulation of cell proliferation, endothelial mesenchymal transition and cancer progression. Thus, overexpression of ZIP4 is considered a malignant factor for pancreatic cancer progression.
Application Details
- Application: Western Blottting, Immunostaining
Handling
References
- • Li et al. 2007. Proc Natl Acad Sci U S A. 104(47):18636-41. PMID 18003899.