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Contributor Information

  • Name Keith Willison
  • Institute The Institute of Cancer Research

Tool Details

  • Tool name: Anti-CCT alpha [22245A1]
  • Alternate names: AI528772, c-cpn, CCT alpha, CCT, CCT-alpha, CCT1, Ccta, CCTalpha, D6S23E, MGC133746, p63, T complex 1, T complex protein 1 alpha subunit, T complex protein 1, T-complex homolog TCP1, T-complex protein 1 subunit alpha, T-complex protein 1 subunit alpha B, Tailless complex polypeptide 1, Tailless complex polypeptide 1A, Tailless complex polypeptide 1B, TCP 1 alpha
  • Clone: 22245A1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Bovine ; Chicken ; Hamster ; Mouse ; Rat ; Rabbit ; Sheep
  • Host: Mouse
  • Molecular weight of the target: 60 kDa
  • Application: WB
  • Strain: Balb/c
  • Description: CCT alpha is a molecular chaperone that assists in the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
  • Isotype: IgG2b
  • Research area: Apoptosis and autophagy; Cancer; Cell biology; Immunology

  • For Research Use Only

Target Details

  • Target: CCT alpha
  • Target molecular weight: 60 kDa
  • Target background: CCT alpha is a molecular chaperone that assists in the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Gao et al. 2013. J Biol Chem. 288(36):25760-8. PMID: 23888055.
  • •  Splice isoforms of phosducin-like protein control the expression of heterotrimeric G proteins.