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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-ELOVL5 [Z88]
  • Alternate names: Elongation of very long chain fatty acids protein 5; ELOVL5; 3-keto acyl-CoA synthase ELOVL5; ELOVL FA elongase 5; Fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 5
  • Clone: Z88
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Strain: Balb/c
  • Description: This protein is involved in the elongation of long-chain polyunsaturated fatty acids functioning as a condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. It may also participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum.
  • Immunogen: Peptide Sequence NNVKPRKLR (peptide immunogen is identical in primates)
  • Isotype: IgG
  • Research area: Cell signaling and signal transduction; Tissue-specific biology
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: ELOVL Fatty Acid Elongase 5
  • Target background: This protein is involved in the elongation of long-chain polyunsaturated fatty acids functioning as a condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. It may also participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.
  • •  The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. Alnabulsi et al. 2019. Int J Cancer. :. PMID: 30737786.