Product Image

Contributor Information

  • Name Bernhard B. Singer
  • Institute LeukoCom

Tool Details

  • Tool name: Anti-CEACAM3/5 (CD66d/e) [308/3-3]
  • Alternate names: CD66d, CD66e
  • Clone: 308/3-3
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 30, 180
  • Application: ELISA ; FACS ; IP ; WB
  • Strain: Balb/c
  • Description: Monoclonal antibody directed against a shared epitope between CEACAM3 and 5. Background and Research Application Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 3/5 belong to the immunoglobulin superfamily. These proteins contain 1 Ig-like V-type (immunoglobulin-like) domain and the cytosolic domain is involved in S100A9 interaction. CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis. CEACAM molecules play a crucial role within the innate immune system, via phagocytosis and pathogen clearance. This antibody reacts with an antigen epitope shared by CEACAM 3 and 5.
  • Immunogen: Recombinant soluble human CEACAM3-Fc produced in HEK293 cells
  • Immunogen UniProt ID: P40198
  • Isotype: IgG1 kappa
  • Research area: Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: CEACAM3/5, CD66d, CD66e
  • Target molecular weight: 30, 180
  • Target background: Monoclonal antibody directed against a shared epitope between CEACAM3 and 5. Background and Research Application Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 3/5 belong to the immunoglobulin superfamily. These proteins contain 1 Ig-like V-type (immunoglobulin-like) domain and the cytosolic domain is involved in S100A9 interaction. CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis. CEACAM molecules play a crucial role within the innate immune system, via phagocytosis and pathogen clearance. This antibody reacts with an antigen epitope shared by CEACAM 3 and 5.

Application Details

  • Application: ELISA ; FACS ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-Ferret immunoglobulin (IgH) [GK1-2-6-B5]

#153924
Product Image

Anti-Cereblon [3B12F7]

#157947
Product Image

Anti-CD44v6 [2F10]

#151573