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Contributor Information

  • Name Roy Jefferis
  • Institute Absolute Antibody ; University of Birmingham

Tool Details

  • Tool name: Anti-CD70 [BU69] rAb
  • Alternate names: CD7 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD7; Ki-24 Antigen; CD7 Antigen; TNLG8A
  • Clone: BU69
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Recombinant
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IP
  • Description: CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis. BU69 inhibits T cell proliferation induced by dendritic cells.
  • Immunogen: Waldenstroms macroglobulineamia cell line WM-1
  • Isotype: IgG1
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: CD70
  • Target background: CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis. BU69 inhibits T cell proliferation induced by dendritic cells.

Application Details

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Original hybridoma first published in: Ito et al. 1999. J Immunol. 163(3):1409-19. PMID: 10415041.