ANTIBODIES

Contributor Information
- Name Roy Jefferis
- Institute Absolute Antibody ; University of Birmingham
Tool Details
- Tool name: Anti-CD70 [BU69] rAb
- Alternate names: CD7 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD7; Ki-24 Antigen; CD7 Antigen; TNLG8A
- Clone: BU69
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Recombinant
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IP
- Description: CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis. BU69 inhibits T cell proliferation induced by dendritic cells.
- Immunogen: Waldenstroms macroglobulineamia cell line WM-1
- Isotype: IgG1
- Research area: Immunology
- For Research Use Only
Target Details
- Target: CD70
- Target background: CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis. BU69 inhibits T cell proliferation induced by dendritic cells.
Application Details
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS
- Shipping conditions: Shipping at 4°C
References
- • Original hybridoma first published in: Ito et al. 1999. J Immunol. 163(3):1409-19. PMID: 10415041.