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Contributor Information

  • Name Margaret Goodall
  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-CD55 [BU97]
  • Alternate names: Complement decay-accelerating factor; CD55; Decay accelerating factor; DAF
  • Clone: BU97
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC
  • Strain: Balb/c
  • Description: Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.
  • Isotype: IgG2b
  • Research area: Cell biology; Cancer; Immunology

  • For Research Use Only

Target Details

  • Target: CD97 ligand
  • Target background: Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection.

Application Details

  • Application: IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Leucocyte Typing VI, 1998, Kishimoto_T. Garland Publishing, NY.
  •   Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.
  •   Origin and properties of soluble CD21 (CR2) in human blood.
  •   Buescher et al. 1991. Public Health Rep. 106(3):333-8. PMID: 1905057.
  •   Problems in estimating the number of women in need of subsidized prenatal care.