ANTIBODIES
Contributor Information
- Name Margaret Goodall
- Institute University of Birmingham
Tool Details
- Tool name: Anti-CD11a [BU85]
- Alternate names: Integrin alpha L; lymphocyte function-associated antigen 1 alpha polypeptide; ITGAL; cell differentiation 11a
- Clone: BU85
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: CD11A encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. This L-domain containing alpha integrin combines with the beta 2 chain to form the integrin lymphocyte function-associated antigen-1 expressed on all leukocytes and this plays a central role in leukocyte intercellular adhesion through interactions with its ligands.
- Isotype: IgG2a
- Research area: Cell biology; Cell signaling and signal transduction; Immunology; Stem cell biology
- For Research Use Only
Target Details
- Target: CD11a
- Target background: CD11A encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. This L-domain containing alpha integrin combines with the beta 2 chain to form the integrin lymphocyte function-associated antigen-1 expressed on all leukocytes and this plays a central role in leukocyte intercellular adhesion through interactions with its ligands.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
References
- • Leucocyte Typing IV, (1989): edited by W. Knapp, OUP, Oxford.
- • Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.
- • Leucocyte Typing VI, (1998): edited by T. Kishimoto, Garland Publishing, New York.
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