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Contributor Information

  • Name Lionel Crawford
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-SV40T [Pab 430]
  • Clone: Pab 430
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Virus
  • Host: Mouse
  • Application: IP ; RIA ; WB
  • Description: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
  • Immunogen: SV40 transformed mouse cells
  • Isotype: IgG3
  • Research area: Cancer; Microbiology

  • For Research Use Only

Target Details

  • Target: Simian virus (SV40) T antigen (large T and small T antigen)
  • Target background: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.

Application Details

  • Application: IP ; RIA ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Kennedy et al. 1985. J Exp Med. 161(6):1432-49. PMID: 2409201.
  •   Suppression of in vivo tumor formation induced by simian virus 40-transformed cells in mice receiving antiidiotypic antibodies.
  •   Harlow et al. 1981. J Virol. 39(3):861-9. PMID: 6169844.
  •   Monoclonal antibodies specific for simian virus 40 tumor antigens.