ANTIBODIES

Contributor Information
- Name Lionel Crawford
- Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
- Tool name: Anti-SV40T [Pab 430]
- Clone: Pab 430
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: IP ; RIA ; WB
- Description: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
- Immunogen: SV40 transformed mouse cells
- Isotype: IgG3
- Research area: Cancer; Microbiology
- For Research Use Only
Target Details
- Target: Simian virus (SV40) T antigen (large T and small T antigen)
- Target background: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
Application Details
- Application: IP ; RIA ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
References
- • Kennedy et al. 1985. J Exp Med. 161(6):1432-49. PMID: 2409201.
- • Suppression of in vivo tumor formation induced by simian virus 40-transformed cells in mice receiving antiidiotypic antibodies.
- • Harlow et al. 1981. J Virol. 39(3):861-9. PMID: 6169844.
- • Monoclonal antibodies specific for simian virus 40 tumor antigens.