ANTIBODIES

Contributor Information
- Name Ayham Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-SPATA25 [Z37P3H11*B2]
- Alternate names: Testis-specific gene 23 protein
- Clone: Z37P3H11*B2
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 23
- Application: ELISA ; IHC ; WB
- Strain: Balb/c
- Description: SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception.
- Immunogen: Peptide Sequence ĂÂ LVRSKRGQP
- Isotype: IgG
- Research area: Developmental biology
- Myeloma used: P3X63Ag8.653
- For Research Use Only
Target Details
- Target: Spermatogenesis Associated 25 (SPATA25)
- Target molecular weight: 23
- Target background: SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception.
Application Details
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC