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Contributor Information

  • Institute A*STAR Accelerate Technologies Pte Ltd

Tool Details

  • Tool name: Anti-M1 [1G1A12]
  • Clone: 1G1A12
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Virus
  • Host: Mouse
  • Application: ELISA ; IF ; Fn ; WB
  • Description: The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and a crucial role in virus assembly and budding.
  • Immunogen: GST-M1 fusion protein
  • Isotype: IgG1 kappa
  • Research area: Microbiology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Influenza A virus matrix 1 protein
  • Target background: The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and a crucial role in virus assembly and budding.

Application Details

  • Application: ELISA ; IF ; Fn ; WB

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Barnwal et al. 2015. Antiviral Res. 116:55-61. PMID: 25666762.
  • •  A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication.