ANTIBODIES

Contributor Information
- Name Patrick Varga-Weisz
- Institute Marie Curie Research Institute
Tool Details
- Tool name: Anti-ACF1 [mACF1]
- Clone: mACF1
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Mouse
- Host: Rabbit
- Molecular weight of the target: 178 kDa
- Application: IF ; IP ; WB
- Description: ACF1 is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex. In the ACF complex, mACF1 influences the nucleosome remodelling activity of the SNF2h ATPase. In the CHRAC complex, mACF1 is thought to target CHRAC to heterochromatin. The ACF1 protein in mouse has several conserved domains including a bromodomain, BAZ, PHD finger, WAC, and WAKZ.
- Immunogen: Peptide coupled to keyhole limpet hemocyanin
- Research area: Genetics
- For Research Use Only
Target Details
- Target: ATP-dependent Chromatin-remodeling Factor (ACF1)
- Target molecular weight: 178 kDa
- Target background: ACF1 is a subunit of the ATP-dependent chromatin-remodelling factor (ACF) complex, and the ISWI CHRAC remodelling complex. In the ACF complex, mACF1 influences the nucleosome remodelling activity of the SNF2h ATPase. In the CHRAC complex, mACF1 is thought to target CHRAC to heterochromatin. The ACF1 protein in mouse has several conserved domains including a bromodomain, BAZ, PHD finger, WAC, and WAKZ.
Application Details
- Application: IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: Whole serum
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.
- • WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.
- • Poot et al. 2000. EMBO J. 19(13):3377-87. PMID: 10880450.