ANTIBODIES
Contributor Information
- Institute A*STAR Accelerate Technologies Pte Ltd
Tool Details
- Tool name: Anti-SARS Nucleocaspid [6H3]
- Alternate names: Nucleoprotein, Protein N, SARS coronavirus N protein, SARS CoV
- Clone: 6H3
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: IF ; WB
- Description: Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions.
- Immunogen: GST-N (residues 121-422)
- Isotype: Inconclusive
- Research area: Microbiology
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: SARS coronavirus nucleocapsid protein
- Target background: Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions.
Application Details
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
.svg)
Unit size: 
.svg)
.svg)
