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Contributor Information

  • Name John Kemshead
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-NCAM [UJ13A]
  • Alternate names: Neural Cell Adhesion Molecule; NCAM; CD56 Antigen; MSK39
  • Clone: UJ13A
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 180 kDa, 160 kDa, 120 kDa
  • Application: IF ; WB
  • Description: NCAM, also known as CD56, is a homophillic binding glycoprotein present on a variety of neural cells including neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synatptic plasticity, learning and memory and in the development of the nervous system.
  • Immunogen: 16 week human foetal brain
  • Isotype: IgG1
  • Research area: Cell biology; Cell signaling and signal transduction; Neurobiology; Stem cell biology

  • For Research Use Only

Target Details

  • Target: Neural Cell Adhesion Molecule (NCAM; CD56)
  • Target molecular weight: 180 kDa, 160 kDa, 120 kDa
  • Target background: NCAM, also known as CD56, is a homophillic binding glycoprotein present on a variety of neural cells including neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synatptic plasticity, learning and memory and in the development of the nervous system.

Application Details

  • Application: IF ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Patel et al. 1989. Int J Cancer. 44(6):1062-8. PMID: 2558078.
  • •  Patel et al. 1989. Br J Cancer. 60(6):861-6. PMID: 2481486.
  • •  Monoclonal antibody 3F8 recognises the neural cell adhesion molecule (NCAM) in addition to the ganglioside GD2.
  • •  Monoclonal antibody UJ13A recognizes the neural cell adhesion molecule (NCAM).
  • •  Moss et al. 1988. Lung Cancer. 4, 76-78.
  • •  Allan et al. 1983. Int J Cancer. 31(5):591-8. PMID: 6852977.
  • •  Biological characterization and clinical applications of a monoclonal antibody recognizing an antigen restricted to neuroectodermal tissues.