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Contributor Information

  • Name Phil Lake
  • Institute University College London (UCL)

Tool Details

  • Tool name: Anti-CD90 [T11D7e]
  • Alternate names: Thy-1 Cell Surface Antigen; Thy-1 Antigen; CDw9; CD9
  • Clone: T11D7e
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse ; Rat
  • Host: Mouse
  • Application: FACS ; Fn
  • Description: CD90 (Thy1.1) is a monomorphic determinant in rat but polymorphic in mice. Anti-CD90 [T11D7e] reacts with Thy1.1 mice e.g. AKR and FVB mice, but not Thy1.2 mice such as CBA and BALB/c. Clone T11D7e is useful for removal of T lymphocytes from cell populations by complement mediated cytotoxicity. CD90 is a mesenchymal cell marker
  • Immunogen: Xenogenic rat thymocytes
  • Isotype: IgM
  • Research area: Cell biology; Immunology; Neurobiology; Stem cell biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: CD90, Thy1.1
  • Target background: CD90 (Thy1.1) is a monomorphic determinant in rat but polymorphic in mice. Anti-CD90 [T11D7e] reacts with Thy1.1 mice e.g. AKR and FVB mice, but not Thy1.2 mice such as CBA and BALB/c. Clone T11D7e is useful for removal of T lymphocytes from cell populations by complement mediated cytotoxicity. CD90 is a mesenchymal cell marker

Application Details

  • Application: FACS ; Fn

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Mahanthappa et al. 1996. J Neurosci. 16(15):4673-83. PMID: 8764655.
  • •  Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth.
  • •  Ogasawara et al. 1990. Microbiol Immunol. 34(12):1025-39. PMID: 2098631.
  • •  Fabian et al. 1990. Neurology. 40(3 Pt 1):419-22. PMID: 1690363.
  • •  Uptake of antineuronal IgM by CNS neurons: comparison with antineuronal IgG.
  • •  Ia restriction specificity of KLH-specific T cells from allogeneic bone marrow chimeras is influenced by histocompatibility at the H-2 and minor histocompatibility loci.
  • •  Yasumizu et al. 1988. J Immunol. 141(6):2181-6. PMID: 3049801.
  • •  Development of donor-derived thymic lymphomas after allogeneic bone marrow transplantation in AKR/J mice.
  • •  Lake et al. 1979. Eur J Immunol. 9(11):875-86. PMID: 393521.
  • •  Production and characterization of cytotoxic Thy-1 antibody-secreting hybrid cell lines. Detection of T cell subsets.