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Contributor Information

  • Name
  • Institute Ludwig Institute for Cancer Research

Tool Details

  • Tool name: Anti-CD25 [PC61 5.3]
  • Alternate names: Interleukin 2 Receptor Subunit Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; P55; Insulin-Dependent Diabetes Mellitus 1; CD25 Antigen
  • Clone: PC61 5.3
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rat
  • Application: FACS ; IHC ; IP
  • Description: CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor Î? chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor Î? (CD122) and common Î? chains (CD132) to form the high affinity IL-2R complex.
  • Isotype: IgG1
  • Research area: Immunology; Biochemistry

  • For Research Use Only

Target Details

  • Target: CD25
  • Target background: CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor a chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+T cells termed T regulatory cells. CD25 associates with the IL-2 receptor ? (CD122) and common ? chains (CD132) to form the high affinity IL-2R complex.

Application Details

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Lowenthal et al. 1985. J Immunol. 135(6):3988-94. PMID: 3934270.