ANTIBODIES

Contributor Information
- Name Ayham Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-Cytochrome P450 39A1 [M30P6D6]
- Clone: M30P6D6
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-ÄÂ?-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
- Immunogen: Ovalbumin-conjugated synthetic peptide CRIEYKQRI (C-terminal sequence).
- Isotype: IgG3 kappa
- Research area: Cancer; Tissue-specific biology; Cell signaling and signal transduction; Metabolism
- Myeloma used: P3X63Ag8.653
- For Research Use Only
Target Details
- Target: CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.
- Target background: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-a-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
Application Details
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
References
- • Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
- • Swan et al. 2016. Oncotarget. :. PMID: 27341022.