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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-NSE [NSEP2]
  • Clone: NSEP2
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Strain: Balb/c
  • Description: Neuron specific enolase (NSE, or ?-isozyme of enolase) is found at elevated concentrations in plasma in certain neoplasias, including paediatric neuroblastoma and small cell lung cancer.
  • Immunogen: Immunogen: ovalbumin-conjugated synthetic peptides corresponding to human NSE amino acid sequence:NSE-P2: aa's 271-285 - TGDQLGALYQDFVRD
  • Isotype: IgG1 kappa
  • Research area: Cancer; Cell biology; Developmental biology; Metabolism; Neurobiology; Stem cell biology
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Gamma-isozyme of human enolase (NSE)
  • Target background: Neuron specific enolase (NSE, or ?-isozyme of enolase) is found at elevated concentrations in plasma in certain neoplasias, including paediatric neuroblastoma and small cell lung cancer.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Murray et al. 1993. J Clin Pathol. 46(11):993-6. PMID: 8254105.
  • •  Immunohistochemistry of neurone specific enolase with gamma subunit specific anti-peptide monoclonal antibodies.
  • •  Duncan et al. 1992. J Immunol Methods. 151(1-2):227-36. PMID: 1629611.
  • •  A simple enzyme-linked immunosorbent assay (ELISA) for the neuron-specific gamma isozyme of human enolase (NSE) using monoclonal antibodies raised against synthetic peptides corresponding to isozyme sequence differences.