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Contributor Information

  • Name Shamshad Cockcroft
  • Institute University College London (UCL)

Tool Details

  • Tool name: Anti-PITPb [1C1]
  • Clone: 1C1
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse ; Rat ; Dog
  • Host: Mouse
  • Molecular weight of the target:
  • Application: ELISA ; IF ; WB
  • Description: Mammalian PITP?Ÿ (phosphatidylinositol transfer protein ?Ÿ) is a 272-amino-acid polypeptide capable of transferring PtdIns, PtdCho and SM (sphingomyelin) between membrane bilayers. Ablation of PITP?Ÿ is embryonically lethal. This antibody is specific for both splice variants of PITP?Ÿ but does not recognise PITPa despite the 95% similarity between the two.
  • Immunogen: Whole Rat PITPb protein
  • Isotype: IgG
  • Research area: Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: Rat PITPb
  • Target molecular weight:
  • Target background: Mammalian PITP?Ÿ (phosphatidylinositol transfer protein ?Ÿ) is a 272-amino-acid polypeptide capable of transferring PtdIns, PtdCho and SM (sphingomyelin) between membrane bilayers. Ablation of PITP?Ÿ is embryonically lethal. This antibody is specific for both splice variants of PITP?Ÿ but does not recognise PITPa despite the 95% similarity between the two.

Application Details

  • Application: ELISA ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: RPMI 1640 + 10% FCS + 2mM L-glutamine + penicillin/streptomycin
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Carvou et al. 2010. J Cell Sci. 123:1262-73. PMID: 20332109 Shadan et al. 2008. Traffic. 9:1743-56. PMID: 18636990 Morgan et al. 2006. Biochem J. 398:411-21. PMID: 16780419