ANTIBODIES
Contributor Information
- Institute University of Cambridge
Tool Details
- Tool name: Anti-Aurora A [Aur A]
- Clone: Aur A
- Tool type: Antibodies
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Drosophila
- Host: Rabbit
- Application: WB
- Description: Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control.
- Immunogen: Maltose-binding protein (MBP) fusion proteins
- Isotype: Isotype: inconclusive - negative on both kits (CRT IgG1)
- Research area: Cell biology
- For Research Use Only
Target Details
- Target: Drosophila Aurora A
- Target background: Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control.
Application Details
- Application: WB
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4Ă°C
Documentation
References
- • Barros et al. 2005. J Cell Biol. 170(7):1039-46. PMID: 16186253.
- • Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
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