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Contributor Information

  • Name Joyce Taylor-Papadimitriou
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Integrin a3 [IA3]
  • Clone: IA3
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; Fn
  • Strain: Balb/c
  • Description: Monoclonal antibody with use studying inhibition of cellular adhesion.
  • Immunogen: Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant.
  • Immunogen UniProt ID: P26006
  • Isotype: IgG1
  • Research area: Cell biology; Cancer
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Integrin a3 (CD49c)
  • Target background: Monoclonal antibody with use studying inhibition of cellular adhesion.

Application Details

  • Application: FACS ; IHC ; IF ; Fn

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167.
  • •  Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167.
  • •  Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-1620. PMID: 25668239.
  • •  Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-20. PMID: 25668239.
  • •  Keratins Stabilize Hemidesmosomes through Regulation of ?4-Integrin Turnover.
  • •  Stawikowski et al. 2014. J Biol Chem. 289(31):21591-604. PMID: 24958723.
  • •  Glycosylation modulates melanoma cell a2?1 and a3?1 integrin interactions with type IV collagen.
  • •  Pytlk et al. 2009. Biomaterials. 30(20):3415-27. PMID: 19362364.
  • •  The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering.
  • •  Turner et al. 2006. Circulation. 114(8):820-9. PMID: 16908762.
  • •  Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study.
  • •  Berdichevsky et al. 1994. J Cell Sci. 107 ( Pt 12):3557-68. PMID: 7535787.
  • •  Branching morphogenesis of human mammary epithelial cells in collagen gels.