Product Image

Contributor Information

  • Name Neil Perkins
  • Institute University of Dundee

Tool Details

  • Tool name: Anti-Pinin [Pinin]
  • Clone: Pinin
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Application: ELISA ; IHC ; IF ; IP ; WB
  • Description: Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. Some data suggest that pinin may play a role in epithelial cell adhesion and the IF complex through a direct interaction with the keratin filaments. Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.
  • Immunogen: Recombinant his-tagged protein
  • Research area: Cancer; Genetics

  • For Research Use Only

Target Details

  • Target: Pinin
  • Target background: Pinin is a cell adhesion-associated and nuclear protein that has been shown to localize in the vicinity of intermediate filament (IF) convergence upon the cytoplasmic face of the desmosomal plaque as well as in the nucleus. Some data suggest that pinin may play a role in epithelial cell adhesion and the IF complex through a direct interaction with the keratin filaments. Pinin has also been reported to have a role in RNA processing and transcriptional regulation and is part of the SNARP complex. Together with SNIP1 and other proteins Pinin has a role in regulation of proliferation and cancer.

Application Details

  • Application: ELISA ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-IL31

#158055
Product Image

Anti-CD23 [5E3]

#154770
Product Image

Anti-CD22 [RFB-4]

#152585

References

  • •  Carvalho et al. 2017. J Cell Sci. 130(9):1519-1531. PMID: 28302904.
  • •  Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.
  • •  Bracken et al. 2008. Cancer Res. 68(18):7621-8. PMID: 18794151.
  • •  Regulation of cyclin D1 RNA stability by SNIP1.