ANTIBODIES
Contributor Information
- Institute The Institute of Cancer Research
Tool Details
- Tool name: Anti-Rheb [Rheb 5D5]
- Clone: Rheb 5D5
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human ; Mouse
- Host: Mouse
- Application: IP ; WB
- Description: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP binding proteins. Rheb is expressed at high levels in the brain, but is also found in many other tissues, and can be induced by growth factor stimulation. Rheb triggers activation of the Raf-MEK-MAPK pathway and has an important role in regulating the insulin/Target of rapamycin (TOR) signalling pathway.
- Immunogen: Human Rheb GST fusion
- Isotype: IgG2a
- Research area: Cancer; Cell signaling and signal transduction; Metabolism
- For Research Use Only
Target Details
- Target: Rheb
- Target background: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP binding proteins. Rheb is expressed at high levels in the brain, but is also found in many other tissues, and can be induced by growth factor stimulation. Rheb triggers activation of the Raf-MEK-MAPK pathway and has an important role in regulating the insulin/Target of rapamycin (TOR) signalling pathway.
Application Details
- Application: IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
.svg)
Unit size: 
.svg)
.svg)
