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Contributor Information

  • Name Elisabeth Trivier
  • Institute Cancer Research Technology

Tool Details

  • Tool name: Anti-IFITM1 [IFITM1]
  • Clone: IFITM1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Molecular weight of the target:
  • Application: WB
  • Description: Analyses of gene expression of IFN-inducible transmembrane protein (IFITM) levels revealed high levels of expression in early and late intestinal neoplasm in both mice and humans. IFITM gene expression is rapidly induced after activation of the -catenin signalling and expression is significantly up-regulated specifically in colorectal tumors and thus may be a useful diagnostic tool in these tumors. IFITM1 will recognise all 3 isoforms of IFITMs ( IFITM1, IFITM2 and IFITM3).
  • Immunogen: HKEEHEVAVLGAPPSTILPRST
  • Research area: Cancer; Cell signaling and signal transduction; Immunology; Stem cell biology

  • For Research Use Only

Target Details

  • Target: Interferon-induced transmembrane protein 1
  • Target molecular weight:
  • Target background: Analyses of gene expression of IFN-inducible transmembrane protein (IFITM) levels revealed high levels of expression in early and late intestinal neoplasm in both mice and humans. IFITM gene expression is rapidly induced after activation of the -catenin signalling and expression is significantly up-regulated specifically in colorectal tumors and thus may be a useful diagnostic tool in these tumors. IFITM1 will recognise all 3 isoforms of IFITMs ( IFITM1, IFITM2 and IFITM3).

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Singh et al. 2011. J Virol. 85(1):208-16. PMID: 20980524.
  •   Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.