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Contributor Information

  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-Follicular Dendritic Cell Antigen [BU10]
  • Clone: BU10
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target:
  • Application: FACS ; IHC
  • Strain:
  • Description: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells.
  • Immunogen:
  • Isotype: IgM
  • Research area: Cell biology; Immunology

  • For Research Use Only

Target Details

  • Target: Follicular Dendritic Cell marker
  • Target molecular weight:
  • Target background: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells.

Application Details

  • Application: FACS ; IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Maeda K et al. Dendrtic Cells. 1996. 6: 43-9
  • •  Maeda et al. 2002. J Histochem Cytochem. 50(11):1475-86. PMID: 12417613.
  • •  Immunohistochemical recognition of human follicular dendritic cells (FDCs) in routinely processed paraffin sections.
  • •  Nunez et al. 2001. BMC Immunol. 2:6. PMID: 11504561.
  • •  Flow cytometric assessment of the reactivity of a panel of monoclonal antibodies (mAb) against two populations of human dendritic cells (DC).
  • •  Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.
  • •  Origin and properties of soluble CD21 (CR2) in human blood.
  • •  Johnson et al. 1986. Clin Exp Immunol. 64(1):205-13. PMID: 3524917.
  • •  Human follicular dendritic cells (FDC): a study with monoclonal antibodies (MoAb).