ANTIBODIES

Contributor Information
- Name Margaret Goodall ; D.L. Hardie ; Roy Jefferis ; Ian MacLennen
- Institute University of Birmingham
Tool Details
- Tool name: Anti-Rough ER Component [BU18]
- Clone: BU18
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Host: Mouse
- Strain: Balb/c
- Description: All eukaryotic cells have an endoplasmic reticulum (ER). Its membrane typically constitutes more than half of the total membrane of an average animal cell. The ER is organized into a netlike labyrinth of branching tubules and flattened sacs extending throughout the cytosol. The tubules and sacs are all thought to interconnect, so that the ER membrane forms a continuous sheet enclosing a single internal space. This highly convoluted space is called the ER lumen or the ER cisternal space, and it often occupies more than 10% of the total cell volume. The ER membrane separates the ER lumen from the cytosol, and it mediates the selective transfer of molecules between these two compartments.
- Isotype: IgG1
- Research area: Cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Rough endoplasmic reticulum component
- Target background: All eukaryotic cells have an endoplasmic reticulum (ER). Its membrane typically constitutes more than half of the total membrane of an average animal cell. The ER is organized into a netlike labyrinth of branching tubules and flattened sacs extending throughout the cytosol. The tubules and sacs are all thought to interconnect, so that the ER membrane forms a continuous sheet enclosing a single internal space. This highly convoluted space is called the ER lumen or the ER cisternal space, and it often occupies more than 10% of the total cell volume. The ER membrane separates the ER lumen from the cytosol, and it mediates the selective transfer of molecules between these two compartments.
Application Details
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: RPMI 1640 + 10% FCS
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC