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Contributor Information

  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-Follicular Dendritic Cell Antigen [BU57]
  • Clone: BU57
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC
  • Description: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells.
  • Isotype: IgM
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: Follicular dendritic cell marker
  • Target background: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells.

Application Details

  • Application: FACS ; IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Maeda K et al. Dendrtic Cells. 1996. 6: 43-9
  •   Maeda et al. 2002. J Histochem Cytochem. 50(11):1475-86. PMID: 12417613.
  •   Immunohistochemical recognition of human follicular dendritic cells (FDCs) in routinely processed paraffin sections.
  •   Ling et al. 1998. Clin Exp Immunol. 113(3):360-6. PMID: 9737663.
  •   Origin and properties of soluble CD21 (CR2) in human blood.
  •   Johnson et al. 1986. Clin Exp Immunol. 64(1):205-13. PMID: 3524917.
  •   Human follicular dendritic cells (FDC): a study with monoclonal antibodies (MoAb).