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Contributor Information

  • Name Birgit Lane
  • Institute Queen Mary University of London

Tool Details

  • Tool name: Anti-Keratin14 [LL002]
  • Clone: LL002
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse ; Pig
  • Host: Mouse
  • Molecular weight of the target: 50 kDa
  • Application: FACS ; IHC ; IF ; WB
  • Strain: Balb/c
  • Description: Monoclonal antibody directed keratin 14, with use in identifying squamous cell carcinoma, and distinguishing basal breast carcinomas.
  • Immunogen: The last 16 carboxy-terminal amino acids of human keratin, in the form of a synthetic peptide. This was coupled to thyroglobulin by the extra Cys added at the N terminus.
  • Immunogen UniProt ID: P02533
  • Isotype: IgG3
  • Research area: Cell signaling and signal transduction
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Keratin 14
  • Target molecular weight: 50 kDa
  • Target background: Monoclonal antibody directed keratin 14, with use in identifying squamous cell carcinoma, and distinguishing basal breast carcinomas.

Application Details

  • Application: FACS ; IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Hagiyama et al. 2017. Front Physiol. 8:997. PMID: 29259558.
  • •  Kuga et al. 2016. Sci Rep. 6:26557. PMID: 27222304.
  • •  Haikala et al. 2016. Cell Cycle. 15(3):316-23. PMID: 26873145.
  • •  Bohn et al. 2010. Int J Clin Exp Pathol. 3(6):600-7. PMID: 20661408.
  • •  p16INK4a expression in basal-like breast carcinoma.
  • •  Kurzrock et al. 2008. Am J Physiol Renal Physiol. 294(6):F1415-21. PMID: 18367656.
  • •  Label-retaining cells of the bladder: candidate urothelial stem cells.
  • •  Purkis et al. 1990. J Cell Sci. 97 ( Pt 1):39-50. PMID: 1701769.
  • •  Antibody markers of basal cells in complex epithelia.
  • •  Schaafsma et al. 1990. Am J Pathol. 136(2):329-43. PMID: 1689541.
  • •  Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on changing expression patterns during tumor progression.