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Contributor Information

  • Name Karen Pulford
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-LSP1 [TPD153]
  • Clone: TPD153
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IP ; WB
  • Description: Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII).
  • Immunogen: Tonsil cells
  • Isotype: IgG1 kappa
  • Research area: Cell signaling and signal transduction; Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Lymphocyte Specific Protein-1 (LSP1)
  • Target background: Human lymphocyte-specific protein 1 is an F-actin binding phosphoprotein, which has an acidic N-terminal half and a basic C-terminal half. In the basic C-terminal half, there are amino acid sequences highly homologous to the actin-binding domains of two known F-actin binding proteins: caldesmon and the villin headpieces (CI, CII, VI, VII).

Application Details

  • Application: IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Marafioti et al. 2004. Haematologica. 89(8):957-64. PMID: 15339679.
  • •  Leukocyte-specific phosphoprotein-1 and PU.1: two useful markers for distinguishing T-cell-rich B-cell lymphoma from lymphocyte-predominant Hodgkin's disease.
  • •  Marafioti et al. 2003. Br J Haematol. 120(4):671-8. PMID: 12588355.
  • •  Leucocyte-specific protein (LSP1) in malignant lymphoma and Hodgkin's disease.
  • •  Pulford et al. 1999. Immunology. 96(2):262-71. PMID: 10233704.
  • •  Lymphocyte-specific protein 1: a specific marker of human leucocytes.