ANTIBODIES

Contributor Information
- Name Karen Pulford
- Institute University of Oxford
Tool Details
- Tool name: Anti-CD20 [PDR78]
- Alternate names: Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains Subfamily A Member 1; Leukocyte Surface Antigen Leu-16; CD2 Antigen; CD2; Bp35; B-Lymphocyte Cell-Surface Antigen B1
- Clone: PDR78
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC
- Description: CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.
- Immunogen: Pokeweed mitogen-activated Burkitt's lymphoma cell lines.
- Isotype: IgG
- Research area: Cancer; Cell biology; Immunology; Stem cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: CD20
- Target background: CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.
Application Details
- Application: FACS ; IHC
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.