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Contributor Information

  • Name Karen Pulford
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-CD20 [PDR78]
  • Alternate names: Membrane Spanning 4-Domains A1; Membrane-Spanning 4-Domains Subfamily A Member 1; Leukocyte Surface Antigen Leu-16; CD2 Antigen; CD2; Bp35; B-Lymphocyte Cell-Surface Antigen B1
  • Clone: PDR78
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC
  • Description: CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.
  • Immunogen: Pokeweed mitogen-activated Burkitt's lymphoma cell lines.
  • Isotype: IgG
  • Research area: Cancer; Cell biology; Immunology; Stem cell biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: CD20
  • Target background: CD20 is a non-Ig differentiation antigen of B cells. Oligomer of CD20 act as calcium channels. It may also be involved in B cell activation and cell cycle progression. CD20 is broadly expressed by normal and neoplastic B cells and absent from all other leucocytes and tissues.

Application Details

  • Application: FACS ; IHC

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Ono N et al. 1997. CD20 Workshop Panel report. In Kishimoto T et al (eds) Leucocyte Typing VI. Garland Publishing Inc., New York and London, p 135-137.