ANTIBODIES

Contributor Information
- Name Karen Pulford
- Institute University of Oxford
Tool Details
- Tool name: Anti-Integrin aX [KB90]
- Clone: KB90
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; WB
- Description: Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnsis of hariy cell leukaemia
- Immunogen: Hairy cell leukaemia cells
- Isotype: IgG1 kappa
- Research area: Cell biology; Cell signaling and signal transduction; Immunology; Stem cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Integrin aX (CD11c; gp150/95 a subunit)
- Target background: Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnosis of hariy cell leukaemia
Application Details
- Application: FACS ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
References
- • In Schlossman SF, et al (eds) 1995. Leucocyte Typing V, Vol 2 Oxford University Press, Oxford, New York and Tokyo, p 2004
- • MacDonald et al. 1986. Immunology. 59(3):427-31. PMID: 2431998.
- • A monoclonal antibody recognizing the p150/95 leucocyte differentiation antigen.