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Contributor Information

  • Name Karen Pulford
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-Integrin aX [KB90]
  • Clone: KB90
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; WB
  • Description: Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnsis of hariy cell leukaemia
  • Immunogen: Hairy cell leukaemia cells
  • Isotype: IgG1 kappa
  • Research area: Cell biology; Cell signaling and signal transduction; Immunology; Stem cell biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Integrin aX (CD11c; gp150/95 a subunit)
  • Target background: Integrin aX is found on hairy cell leukaemias and malignant histiocytes and on tissue macrophages, monocytes, activated neutrophils and some T-cell clones. Integrin aX has utility for diagnosis of hariy cell leukaemia

Application Details

  • Application: FACS ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   In Schlossman SF, et al (eds) 1995. Leucocyte Typing V, Vol 2 Oxford University Press, Oxford, New York and Tokyo, p 2004
  •   MacDonald et al. 1986. Immunology. 59(3):427-31. PMID: 2431998.
  •   A monoclonal antibody recognizing the p150/95 leucocyte differentiation antigen.