ANTIBODIES
Contributor Information
- Name Stephen West
- Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
- Tool name: Anti-Rad51 [SWE26]
- Clone: SWE26
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Polyclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Rabbit
- Application: IP ; WB
- Description: Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing 2 and 3) are Rad51 paralogs and are also components of the homologous recombination pathway.
- Immunogen: Human Rad51 N-Terminal region Peptide C. (VEEESFGPQPISRLE) linked to KLH
- Research area: Genetics
- For Research Use Only
Target Details
- Target: Rad51
- Target background: Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologues recombination DNA repair pathway. Rad51 forms a nucleoprotein filament through binding Rad52 and single stranded DNA that are exposed following double strand breaks. This filament initiates recombination. Rad 51B, Rad51C, Rad51D, XRCC2 and XRCC3 (X-Ray Repair Cross Complementing 2 and 3) are Rad51 paralogs and are also components of the homologous recombination pathway.
Application Details
- Application: IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: Whole serum
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
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